The Cantor Research Laboratory

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The broad interests of the Cantor Laboratory are to elucidate the gene regulatory mechanisms involved in normal blood cell development and to understand how their dysregulation leads to certain human blood disorders. This involves studies of hematopoietic transcription factors, chromatin remodeling complexes, epigenetics, chromatin architecture, signal transduction, stem cell self-renewal, cell fate decisions and terminal cell maturation. Our work pertains to human leukemias, myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPNs), congenital dyserythropoieitic anemias/thrombocytopenias, sickle cell disease, and thalassemia.